Found within every tablet of Femalegra 100mg, Sildenafil Citrate is the pharmacologically active component responsible for its therapeutic effect. This is completely normal as they contain the same active ingredient. It is used to support blood flow and treat certain circulatory conditions. Because research into its use in women is still ongoing, clinical investigation has not yet produced sufficient evidence to support routine prescribing in this group, meaning that a registered UK healthcare professional must always be consulted before this medicine is taken.
Because Sildenafil is marketed under multiple brand names, patients who have been prescribed it may come across different product names during their treatment. Femalegra 100 is one such brand containing Sildenafil Citrate at a 100mg strength.
Many patients are unfamiliar with this name. They may know Sildenafil better through its reference brand, Viagra. Patients are better equipped to engage with their treatment safely when the medicine’s purpose and mechanism are clearly understood.
This guide covers what Femalegra 100 is, how Sildenafil works, and what safety considerations UK patients should be aware of. Before any new medicine is started, guidance must be sought from a doctor or pharmacist, as this step is essential for safe and appropriate use.
Learn more about PDE5 inhibitor treatments available through regulated pharmacies.
Important Notice for Women
A licence for the use of Femalegra 100 in women has not been granted by the MHRA, meaning that its prescription in this group falls outside the scope of approved clinical indications. Its safety and effectiveness in treating female sexual dysfunction have not been fully established. Because self-medicating with this product carries serious health risks, it must only be taken under direct medical supervision, where a prescriber can assess suitability and monitor safety.
What Is Femalegra 100?
Femalegra 100mg is a tablet containing Sildenafil Citrate. Classified within the phosphodiesterase-5 (PDE5) inhibitor group, this medicine acts by relaxing blood vessels, which improves circulation and supports the therapeutic effect. They are primarily associated with treating erectile dysfunction in men but have broader clinical applications.
Is Femalegra 100 Suitable for Women?
In the UK, no licence has been granted for Femalegra 100 in women, as the MHRA has not authorised Sildenafil Citrate for the treatment of female sexual dysfunction.
Clinical trials in women remain ongoing. Evidence of its safety and effectiveness in women is still limited and inconclusive.
Some doctors may prescribe it off-label. This means outside its licensed use, and only after a thorough medical assessment.
Women must never take Femalegra 100 without a doctor’s prescription. Self-medicating with unlicensed medicines is unsafe and potentially dangerous.
Medicine Summary Table
| Detail | Information |
|---|---|
| Brand Name | Femalegra 100 |
| Active Ingredient | Sildenafil Citrate |
| Drug Class | PDE5 Inhibitor |
| Strength | 100mg |
| Manufacturer | Sunrise Remedies |
| Prescription Status | Prescription-only medicine (POM) |
| UK Reference Brand | Viagra |
How Sildenafil Works in the Body
By inhibiting phosphodiesterase type 5 (PDE5), Sildenafil prevents the breakdown of cyclic GMP, a chemical that plays a key role in vascular relaxation and blood flow regulation.
Because the PDE5 enzyme is inhibited by Sildenafil, cyclic GMP accumulates within the smooth muscle of blood vessel walls, producing a vasodilatory effect. As a result of cyclic GMP accumulation, smooth muscle tissue relaxes and blood vessels are widened, allowing improved circulation to the targeted area.
In men, this increased blood flow supports erectile function during sexual stimulation. In women, research suggests similar vascular effects may occur in genital tissue. Because clinical evidence supporting its use in women remains both limited and inconclusive, this medicine is not routinely recommended for female patients without specialist guidance.
When a Doctor May Consider Prescribing Femalegra 100
Sildenafil, the active ingredient in Femalegra 100, has several established clinical uses.
Doctors in the UK may prescribe it for the following conditions:
Erectile dysfunction (ED)
In adult men, erectile dysfunction (ED) is an established primary indication for Sildenafil, where it is recognised as a first-line treatment option supported by extensive clinical evidence. Sildenafil supports the ability to achieve and maintain an erection during sexual stimulation, meaning that arousal must be present for the medicine to take effect.
Pulmonary arterial hypertension (PAH)
In the UK, Sildenafil holds a licence for the treatment of pulmonary arterial hypertension (PAH), where it is used to reduce strain on the heart by relaxing the pulmonary blood vessels. It reduces blood pressure in the pulmonary arteries and improves exercise capacity.
Female sexual dysfunction (investigational)
Some clinicians explore Sildenafil’s role in female arousal disorders. However, this use is not currently licensed in the UK. Any such prescribing would be off-label and must involve full informed consent.
See available treatment options for sexual health and circulatory conditions at regulated pharmacies.
Benefits of Femalegra 100
Improved blood flow and circulation
Because its mechanism of action is well established, Sildenafil is widely recognised as an effective agent for improving vascular blood flow in both licensed indications. For conditions like PAH, this translates into measurable clinical benefit. Reduced breathlessness and improved exercise tolerance are among the clinical benefits most commonly reported by patients using Sildenafil for pulmonary arterial hypertension.
Fast onset of action
Because its onset of action occurs within 30 to 60 minutes of being taken, Sildenafil offers a degree of timing flexibility that is valued by patients managing treatment around daily activities.
A Thoroughly Characterised Safety Profile
Decades of clinical use have generated a detailed understanding of Sildenafil’s risks and benefits, allowing doctors and pharmacists to adapt treatment responsibly to each individual patient.
Alternative Treatments a Doctor May Discuss
Depending on individual patient needs and health profile, other PDE5 inhibitors may be considered as suitable alternatives by the prescribing doctor.
These Include:
Tadalafil (Cialis)
Tadalafil (Cialis): Offering a duration of action of up to 36 hours, Tadalafil is also available as a once-daily low-dose option, which makes it a preferred choice for patients who value greater flexibility in timing.
Vardenafil (Levitra)
Vardenafil is another PDE5 inhibitor with a similar mechanism of action. For patients in whom an adequate response to Sildenafil has not been achieved, alternative PDE5 inhibitors may be considered by the prescribing doctor as a more appropriate option.
Avanafil (Spedra)
Avanafil has a faster onset than Sildenafil. For patients who require a faster onset, alternative PDE5 inhibitors with a shorter time to effect may be recommended by their prescribing doctor.
Your doctor will assess your medical history before recommending any specific treatment. Further information on PDE5 inhibitor medicines is available in our comparative guide.
Possible Side Effects of Femalegra 100
Like any medicine, Sildenafil can cause side effects, though not every patient who takes it will be affected in the same way.
| Side Effect | Description |
|---|---|
| Facial flushing | Redness and warmth |
| Headache | — |
| Dyspepsia | Indigestion or stomach discomfort |
| Nasal congestion | — |
| Dizziness | — |
| Blurred vision | — |
These effects are generally mild and short-lived. Because these reactions are typically short-lived, they tend to resolve without intervention as Sildenafil is cleared from the body.
| Side Effect | Details |
|---|---|
| Vision Loss | Abrupt loss of vision affecting one or both eyes |
| Hearing Loss | Sudden hearing loss or tinnitus |
| Cardiac Symptoms | Chest pain or an irregular heartbeat |
| Priapism | A painful erection persisting beyond four hours |
| Blood Pressure | A marked and sudden reduction in blood pressure |
Because serious side effects require prompt intervention, the medicine must be stopped immediately if any occur, and a doctor must be contacted without delay or 999 called in an emergency.
Important Safety Advice
This section contains essential information. Please read it carefully before taking Femalegra 100.
Drug Interactions
Sildenafil interacts with several medicines. These interactions can be dangerous.
Because the combination carries the risk of a sudden and dangerous drop in blood pressure, Sildenafil must never be taken alongside nitrate medicines such as glyceryl trinitrate (GTN), which are commonly prescribed for chest pain. When Sildenafil is combined with nitrate medicines, a sudden and severe drop in blood pressure can be triggered, making this combination strictly contraindicated.
When Sildenafil is taken alongside alpha-blockers prescribed for high blood pressure or prostate conditions, an additional reduction in blood pressure may occur, requiring careful clinical assessment before use. Medical supervision is essential.
Known interacting medicines include:
- Amlodipine (calcium channel blocker)
- Carbamazepine (anticonvulsant)
- Dexamethasone (corticosteroid)
- Ketoconazole (antifungal)
- Ritonavir and other HIV protease inhibitors
These must be disclosed to the prescribing doctor and pharmacist, alongside all other medicines currently being taken, including herbal supplements and over-the-counter products, allowing potential interactions to be identified.
Alcohol and Sildenafil
Because both alcohol and Sildenafil independently reduce blood pressure, taking them together can produce an additive effect that increases the risk of dizziness, fainting, and cardiovascular stress. Because combining Sildenafil with alcohol raises the risk of dizziness, fainting, and cardiovascular stress, alcohol intake must be kept to a minimum while this medicine is being used.
Pre-existing Medical Conditions
Tell your doctor if you have or have had any of the following:
- Heart disease, a previous heart attack, or stroke. High or low blood pressure
- Liver or kidney problems
- A history of prolonged erections
- Retinitis pigmentosa or other eye conditions
- Sickle cell anaemia or related blood disorders
A history of blood clots or heart problems, including a heart attack within the past three months or a stroke and heart failure within the past six months, means Sildenafil must not be taken.
Driving and Machinery
Because Sildenafil can cause dizziness and blurred vision, driving or operating machinery must be avoided until the individual response to the medicine is fully understood.
Pregnancy and Breastfeeding
Femalegra 100 is not licensed for use in women. Because the available data on its safety during pregnancy and breastfeeding remain limited, this medicine must not be used in these circumstances without specialist medical advice. Before taking any Sildenafil-containing product during pregnancy or whilst breastfeeding, medical advice must be sought from a doctor.
Dosage Safety
No more than one tablet must be taken within any 24-hour period, as exceeding the prescribed dose raises the risk of serious side effects without providing any additional clinical benefit.
When Is Medical Advice Required?
Contact your GP if you notice any of the following:
- Chest pain occurring during or after sexual activity
- An erection that has persisted for longer than four hours
- Any sudden change in vision or hearing
- Severe dizziness or an episode of fainting
- Signs of an allergic reaction, such as a rash, facial or throat swelling, or breathing difficulty
- No improvement in your condition after several uses
Medical help must not be delayed if any of these symptoms occur.
Is It Safe to Take Femalegra 100 Alongside Other Medicines?
Because certain side effects of Sildenafil require prompt medical attention, any concerns must be raised with a doctor without delay.
Sildenafil has a significant interaction profile. It must be used carefully alongside other medicines.
Always inform your pharmacist of all the medicines you currently take. To ensure safe prescribing, the doctor and pharmacist must be made aware of every medicine currently in use, including prescription items, over-the-counter products, and herbal remedies, allowing a full interaction check to be carried out.
Your pharmacist can identify potential interactions and advise you accordingly. Because dose adjustments without clinical oversight can increase the risk of harm, no change to the prescribed dose must ever be made without first consulting a registered healthcare professional.
Storage and Handling Advice
Store Femalegra 100 tablets at room temperature. Storage and Disposal Advice: Direct heat, sunlight, and moisture must all be avoided when storing this medicine. All medicines must be kept out of the reach and sight of children. Because the original packaging protects tablets from damage and retains the patient information leaflet, storage outside this packaging must be avoided. Because flushing medicines down the toilet or placing them in household waste poses environmental risks, unused tablets must be returned to a local pharmacy for safe disposal.
Responsible Access to Treatment in the UK
You must obtain medicine with a valid prescription from a registered healthcare professional. Because Sildenafil Citrate holds prescription-only medicine (POM) status under UK law, the legal supply of Femalegra 100 is only possible where a valid prescription has been issued by a registered UK healthcare professional.
Because products sourced from unregulated online suppliers may be counterfeit, contaminated, or incorrectly dosed, purchasing prescription medicines through these channels carries serious risks to patient safety.
If you consider that Sildenafil may be relevant to your condition, consult your GP or an NHS sexual health clinic before taking any action.
Frequently Asked Questions
Q: What is the use of Femalegra 100mg?
A: Femalegra 100mg contains Sildenafil Citrate. It supports blood flow in licensed indications; its effects on arousal in women remain under clinical investigation and are not currently established. Because Sildenafil is also licensed for the treatment of pulmonary arterial hypertension, its clinical applications extend beyond erectile dysfunction, meaning that a registered UK healthcare professional must always be consulted before use.
Q: How many hours does sildenafil 100mg last?
A: With a duration of action of four to six hours, Sildenafil 100mg is taken 30 to 60 minutes before sexual activity, though individual response may vary. No more than one dose must be taken within any 24-hour period.
Q: How to use Femalegra?
A: A single tablet must be swallowed intact with a full glass of water, taken 30 to 60 minutes before sexual activity. Crushing, chewing, or splitting the tablet before swallowing must be avoided, as doing so may affect the medicine’s absorption and efficacy. Because the prescribed dosage instructions reflect individual clinical assessment, they must always be followed precisely as directed by the doctor.
Q: Is Femalegra 100mg safe for women to take?
A: Because its safety profile in women has not yet been fully established, Femalegra 100mg does not hold a licence for use in this group under UK regulatory standards. Because clinical oversight is essential for safe use, this medicine must only be taken under strict medical supervision and with a valid prescription in place.
Conclusion
Femalegra 100 contains Sildenafil Citrate, a well-established PDE5 inhibitor with proven clinical applications. Among its licensed indications, erectile dysfunction in men and pulmonary arterial hypertension represent the two conditions most widely treated with Sildenafil in clinical practice.
Any such use requires careful medical supervision and fully informed patient consent.
Before treatment with Sildenafil is started, every patient must be made aware of its detailed safety and interaction profile, as this knowledge is essential for safe and informed use. Because the risks associated with unsupervised use are clinically significant, medical supervision is an essential requirement and not a matter of personal choice.
Speak to your doctor or a registered UK pharmacist before taking Femalegra 100 or any Sildenafil-containing product.
Femalegra 100 does not hold a licence for use in women from the MHRA or other recognised regulatory authorities. Women considering this medicine must consult their GP first. No woman should take this product without a valid prescription and direct medical guidance.
References
- NHS. (2024). Sildenafil (Viagra) — overview. nhs.uk
- MHRA. (2024). Prescription-only medicines in the UK. gov.uk/mhra
- European Medicines Agency. (2023). Sildenafil — product information summary. ema.europa.eu
Medical Disclaimer
This article is for informational purposes only and does not replace professional medical advice. Always consult a registered healthcare professional before starting or changing any treatment.