Poxet 90 is formulated with 90mg of dapoxetine. Dapoxetine is categorised as a short-acting selective serotonin reuptake inhibitor (SSRI). Premature ejaculation (PE) is the condition for which this prescription-only medicine (POM) is licensed for use in adult men aged 18 to 64. On-demand use is how this medicine is administered. Before sexual activity, this medicine is taken between one and three hours before sexual activity, allowing it sufficient time to take effect. It is not a daily medicine.
Poxet 90 and Priligy: UK Brand Overview
Several brand names carry dapoxetine in the UK. This is completely normal as they contain the same active ingredient. You must obtain medicine with a valid prescription from a registered healthcare professional.
| Feature | Poxet 90 | Priligy (UK Reference Brand) |
|---|---|---|
| Active Ingredient | Dapoxetine | Dapoxetine |
| Strength | 90mg | 30mg / 60mg |
| Drug Class | SSRI (short-acting) | SSRI (short-acting) |
| Licensed Use | Premature ejaculation | Premature ejaculation |
| Prescription Status | POM | POM |
| Suitable Age Range | 18–64 years | 18–64 years |
| Dosing Schedule | On demand | On demand |
Priligy is the MHRA-authorised reference brand for dapoxetine in the UK. Poxet 90 contains the same active ingredient at a higher strength of 90mg. Both must be accessed only with a valid prescription from a pharmacist.
How Dapoxetine Works in the Body
Within the selective serotonin reuptake inhibitor (SSRI) class, dapoxetine falls within the selective serotonin reuptake inhibitor (SSRI) pharmacological class, distinguishing it from daily-use SSRIs. Unlike conventional SSRIs prescribed for depression, dapoxetine has a rapid onset of action and a short half-life. Because it acts quickly and clears the body rapidly, on-demand dosing is supported rather than a daily schedule.
At neuronal synapses, serotonin reuptake is blocked by dapoxetine, which raises serotonin availability in the nervous system. This increases serotonin activity in specific regions of the central nervous system that regulate the ejaculatory reflex. The result is a measurable delay in ejaculation and improved voluntary control during sexual activity.
The medicine reaches peak plasma concentration within approximately one to two hours of ingestion. It is then rapidly cleared from the body, which is why it is taken as needed rather than prescribed as a daily treatment. This pharmacokinetic profile distinguishes it from other SSRIs used in psychiatry.
Clinical Uses
Poxet 90 is licensed for a specific and defined clinical indication. Prescribers must confirm eligibility before initiating treatment.
Poxet 90 is indicated for:
This medicine is used to treat premature ejaculation (PE) in men aged 18 to 64 years. The goal of treatment is to improve ejaculatory control. PE is characterised by ejaculation occurring with minimal stimulation and earlier than desired. PE causes personal distress or interpersonal difficulty. Cases where PE has been formally assessed and confirmed by a healthcare professional
Poxet 90 is not indicated for:
Men under 18 or over 64 years of age, women, or use during pregnancy, erectile dysfunction or other sexual health conditions as a standalone treatment, daily or prophylactic use without medical direction
Doctors will assess the full clinical picture before prescribing. Where a concurrent condition, such as erectile dysfunction, is present, this must be addressed alongside PE management.
Safety Information
| Category | Side Effect | Details |
|---|---|---|
| Common Side Effects (may affect more than 1 in 10 men) | Nausea | Generally mild and short-lived |
| Headache | Often reduces after the first few doses | |
| Dizziness | Often reduces after the first few doses | |
| Diarrhoea | Generally mild and short-lived | |
| Fatigue (tiredness) | Generally mild and short-lived | |
| Serious Side Effects (seek urgent medical attention) | Fainting or loss of consciousness | Particularly when standing up quickly |
| Chest pain | Requires immediate medical attention | |
| Irregular or rapid heartbeat | Requires immediate medical attention | |
| Severe allergic reaction | Signs include rash, facial swelling, swelling of the lips or throat, or difficulty breathing | |
| Severe confusion | May signal a serious reaction — seek immediate medical attention | |
| Sudden mood changes | May signal a serious reaction — seek immediate medical attention | |
| Marked agitation | May signal a serious reaction — seek immediate medical attention | |
| Seizures | Requires urgent medical attention |
MHRA Yellow Card Scheme
If you experience a side effect whilst taking Poxet 90, you can report it directly to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. By reporting side effects, the safety of medicines is improved for every patient across the UK.
Safety Advice
Drug Interactions
Poxet 90 must not be taken alongside monoamine oxidase inhibitors (MAOIs), thioridazine, lithium, linezolid, tramadol, triptans used for migraines, nefazodone, tryptophan, or St John’s Wort. Serotonin syndrome and other life-threatening reactions may be triggered by taking certain medicines together. These risks are serious and must not be overlooked.
Use with particular caution alongside antifungal medicines such as ketoconazole or itraconazole, HIV medicines including ritonavir and saquinavir, antibiotics such as telithromycin, medicines for erectile dysfunction including sildenafil, tadalafil, and vardenafil, blood-thinning medicines such as warfarin, and anti-inflammatory medicines including ibuprofen. Always present your full list of medicines to your prescriber and pharmacist before starting treatment.
Alcohol and Recreational Substances
Do not consume alcohol whilst taking Poxet 90. Because alcohol lowers blood pressure and impairs balance, the risk of dizziness and fainting is significantly raised when alcohol is taken alongside this medicine. Recreational substances, including ecstasy, LSD, narcotics, and benzodiazepines, can cause dangerous interactions. Disclose all substance use honestly to your prescribing doctor.
Grapefruit Juice
For at least 24 hours prior to taking Poxet 90, grapefruit juice must be avoided entirely. Grapefruit juice inhibits enzymes that metabolise dapoxetine, potentially raising its plasma levels to potentially unsafe concentrations.
Driving and Operating Machinery
Dizziness, blurred vision, and reduced concentration are among the effects that may be experienced with Poxet 90. Because concentration and coordination may be affected following a dose, driving or operating heavy machinery poses a significant risk and must be avoided. These effects may occur even within recommended doses, particularly when first starting treatment.
Mental Health Conditions
Tell your doctor if you have or have had any of the following: a personal history of depression, mania, bipolar disorder, or schizophrenia. Dapoxetine may not be appropriate in the presence of these conditions. Contact your doctor promptly if you notice any change in mood or mental state during treatment.
Contraindications
Do not take Poxet 90 if you have heart failure, abnormal heart rhythm, liver problems, a history of fainting, or a history of mania or severe depression. Also disclose any history of bleeding disorders, kidney problems, epilepsy, or raised intraocular pressure (glaucoma) before starting treatment.
Accessing Treatment Responsibly
Being a prescription-only medicine (POM), Poxet 90 is legally required to be dispensed only by a registered pharmacy. You must obtain medicine with a valid prescription from a registered healthcare professional.
Purchasing prescription medicines from unregulated online sources is both unsafe and illegal. Unregulated suppliers cannot guarantee the authenticity, strength, or purity of the medicines they supply.
If you believe you may have premature ejaculation, consult your GP or a registered online clinic. A qualified clinician will assess your suitability for treatment, review your full medical history, and determine whether dapoxetine is appropriate for you. Access treatment only through regulated healthcare channels.
Frequently Asked Questions
Q: What is the use of Poxet 90 mg?
A: This medicine is used to treat premature ejaculation in adult men aged 18 to 64, where ejaculatory control is improved and delay is achieved. The medicine is a prescription medicine in the UK. Learn how it works, its benefits, side effects, and safety advice.
Q: Can I sleep after taking dapoxetine?
A: Sexual activity should be planned for one to three hours after dapoxetine is taken. Sleeping immediately after taking it is not recommended. The best results are achieved when the medicine is taken while you are alert and physically active.
Conclusion
Poxet 90 contains 90mg of dapoxetine as its active SSRI component. Because premature ejaculation affects men differently, this medicine is licensed for on-demand use in adult men aged 18 to 64. By raising serotonin activity within the central nervous system, the medicine prolongs the time to ejaculation and strengthens voluntary control.
Like all prescription medicines, Poxet 90 carries risks and is subject to important contraindications and drug interactions. Because interactions with other substances are possible, all medicines, supplements, and other substances currently being used should be discussed with your prescriber before dapoxetine is started. Medical supervision must be maintained throughout treatment.
Treatment must always be accessed through a registered UK healthcare professional and dispensed by a regulated UK pharmacy. Contact your GP if you notice any concerns arising during treatment. Closely following the guidance given by your doctor is strongly advised.
References
- NHS. Premature ejaculation. Available at: www.nhs.uk
- Public Assessment Report — dapoxetine (Priligy). Available at: www.gov.uk/mhra
Medical Disclaimer
This article is for information purposes only and does not replace professional medical advice. Always consult a registered health professional before starting or changing any treatment. Poxet 90 is a prescription-only medicine and must only be used under the supervision of a registered UK healthcare professional.