Description
Ciplactin Syrup: Cyproheptadine 2mg for Allergies
Ciplactin Syrup each 5ml contains Cyproheptadine Hydrochloride 2mg. It is manufactured by Cipla Limited. It treats allergic symptoms and stimulates appetite, including Ciplactin syrup for medically supervised weight gain. It is a prescription-only medicine (POM). The UK reference brand containing the same active salt is Periactin.

Composition
- Cyproheptadine Hydrochloride – 2 mg per 5 ml
- Excipients – As required
Manufacturer
Cipla Limited
Available Variants
Ciplactin 4 mg
Expiry
Varies by batch; check product label.
Ciplactin Syrup vs Periactin
| Feature | Ciplactin | Periactin |
|---|---|---|
| Active Ingredient | Cyproheptadine Hydrochloride | Cyproheptadine Hydrochloride |
| Strength | 2mg per 5ml | 2mg per 5ml |
| Drug Class | Antihistamine — Piperidine derivative | Antihistamine — Piperidine derivative |
| Mechanism | H1 receptor + serotonin antagonist | H1 receptor + serotonin antagonist |
| POM Status | Yes | Yes |
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Mechanism of Action
Cyproheptadine Hydrochloride blocks histamine H1 receptors, reducing itching, sneezing, and nasal congestion. It also inhibits serotonin receptors that regulate appetite. This increases hunger signals and supports calorie intake. This dual action distinguishes it within the antihistamine class.
Clinical Uses
- Appetite stimulation and Ciplactin syrup for weight gain under medical supervision
- Supportive treatment for unintentional weight loss or undernutrition
- Relief from allergic rhinitis and allergic conjunctivitis
- Management of urticaria (hives) and mild dermatological allergies
- It eases itching, sneezing, and nasal congestion
- Adjunct migraine management under a doctor’s supervision
Safety Information
| Type | Side Effect |
|---|---|
| Common Side Effects | Drowsiness |
| Dry mouth | |
| Mild dizziness | |
| Constipation | |
| Increased appetite | |
| Serious Side Effects ⚠️ | Severe allergic reaction (rash, breathlessness, facial swelling) |
| Extreme drowsiness or confusion | |
| Difficulty urinating |
Stop Ciplactin Syrup immediately if serious symptoms occur. Contact NHS 111 or attend A&E. All suspected adverse reactions can be submitted to the MHRA directly via yellowcard.mhra.gov.uk.
Safety Advice
Liver
Use with caution in liver conditions. Dosage adjustment may be required. Speak to a registered UK healthcare professional before beginning treatment.
Kidney
Patients with kidney disease must use it under medical supervision only. Regular monitoring may be necessary.
Alcohol
Avoid alcohol whilst taking this medicine. It increases sedation, dizziness, and cognitive impairment.
Driving
This medicine may cause drowsiness. Drowsiness is a known effect of Ciplactin Syrup. Use caution when driving or working with machinery whilst taking this medicine.
Pregnancy
Not recommended during pregnancy unless directed by a licensed medical professional.
Breastfeeding
This syrup must only be taken under a doctor’s supervision. Cyproheptadine Hydrochloride may pass into breast milk. Always seek medical advice before taking this syrup whilst breastfeeding.
Accessing Treatment Responsibly
Ciplactin Syrup is a POM in the United Kingdom. Access it only through a GPhC-registered pharmacy. Do not self-prescribe or obtain it from unregulated sources. Speak to your GP or pharmacist to begin the appropriate clinical pathway.
Frequently Asked Questions
Q: What is Ciplactin Syrup used for?
A: This syrup helps ease allergic symptoms. It also supports appetite. Under medical supervision, Ciplactin syrup for weight gain may be taken alongside a balanced diet.
Q: How quickly does Ciplactin work?
A: Ciplactin Syrup typically begins working within 30 minutes to two hours. Appetite improvement may take several days of consistent use. Always follow your prescriber’s dosage instructions.
Q: Can Ciplactin Syrup cause stomach issues?
A: Ciplactin Syrup typically begins working within 30 minutes to two hours. Appetite improvement may take several days of consistent use. Always follow your prescriber’s dosage instructions.
Q: Is Ciplactin an antibiotic?
A: Effects are usually felt within 30 minutes to two hours of taking a dose. Appetite improvement may take several days of consistent use. Always follow your prescriber’s dosage instructions.
Conclusion
Ciplactin Syrup (Cyproheptadine Hydrochloride 2mg per 5ml) by Cipla Limited treats allergic symptoms and supports medically supervised weight gain. It shares the same active salt as the UK reference brand Periactin. As a POM, it must be prescribed through a regulated UK clinical framework. Any unwanted effects should be reported through the MHRA Yellow Card scheme. Access only with a valid prescription through a GPhC-registered pharmacy.
References
- NHS — Antihistamines: www.nhs.uk/conditions/antihistamines
- MHRA Yellow Card: yellowcard.mhra.gov.uk
Medical Disclaimer
This content has been prepared for informational and educational purposes only. Before initiating, adjusting, or discontinuing any medicine, always speak with a registered UK healthcare professional. Never self-diagnose or self-prescribe based on online information.






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