Description
Seroflo 100 Rotacaps: Fluticasone COPD Care
Seroflo 100 Rotacaps contains Fluticasone Propionate (100 mcg) combined with Salmeterol. Designed as a cost-effective bioequivalent to the UK reference brand Seretide, it adheres strictly to established pharmaceutical formulation standards.
Scientific Salt Consistency
| Parameter | Seroflo 100 Rotacaps | Seretide |
|---|---|---|
| Active Ingredient (Salt) | Fluticasone Propionate + Salmeterol | Fluticasone Propionate + Salmeterol |
| Strength | 100mcg | 100mcg |
| Chemical Class | Corticosteroid and LABA | Corticosteroid and LABA |
| Bioequivalence | Bioequivalent | UK Reference Brand |
| Therapeutic Effect | Reduces airway inflammation | Reduces airway inflammation |
Available Strengths
- Seroflo 100 mcg
- Seroflo 250 mcg
- Seroflo 500 mcg
Mechanism of Action
Fluticasone Propionate + Salmeterol works via two active mechanisms. Fluticasone Propionate is an inhaled corticosteroid (a steroid that reduces airway swelling).
A long-acting bronchodilator, meaning a medicine that relaxes airway muscles, is what salmeterol is classed as.
Together, Fluticasone Propionate + Salmeterol improves breathing in chronic lung conditions.

Clinical Uses
- Prophylactic management of asthma (a chronic inflammatory lung disease).
- This medicine offers symptom control for those living with severe COPD, a lung condition that progressively worsens over time.
- Reducing frequent asthma exacerbations (sudden worsening of breathing symptoms).
Safety Information
| Category | Details |
|---|---|
| Common Side Effects | Candidiasis, a fungal infection affecting the mouth and throat |
| — | Tremor (unintentional muscle shaking) and headache |
| — | Throat irritation or hoarseness |
| Serious Side Effects | Paradoxical bronchospasm (sudden tightening of airways after inhalation) |
| — | Severe allergic reactions |
Report adverse reactions via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk).
Safety Advice
Liver
Systemic corticosteroid exposure may be increased where hepatic impairment, meaning reduced liver function, is present. Your doctor will monitor treatment accordingly.
Kidney
No dose adjustment is required for Seroflo Rotacaps 100, even where renal impairment, meaning reduced kidney function, is present.
Alcohol
Alcohol does not directly interact with Fluticasone Propionate + Salmeterol. However, avoid excessive drinking.
Driving
Seroflo 100 Rotacaps has no bearing on your capacity to drive or use machinery safely.
Pregnancy
This medicine should only be used during pregnancy where the benefits outweigh the risks to the foetus (unborn baby).
Breastfeeding
Consult your doctor before using Fluticasone Propionate + Salmeterol whilst breastfeeding.
Any change to treatment, or the start of a new one, calls for advice from a qualified healthcare professional beforehand.
Accessing Treatment Responsibly
Seroflo 100 Rotacaps holds Prescription-Only Medicine (POM) status in the UK, and is used in the management of both asthma and COPD. Patients must access treatment responsibly with a valid prescription through a regulated pharmacy supply following clinical consultation.
FAQ
Q: What is Seroflo 100 Rotacaps used for?
A: Asthma and chronic obstructive pulmonary disease (COPD) are managed using Seroflo 100 Rotacaps. Wheezing, breathlessness, and coughing are prevented as a result, achieved by relaxing airway muscles and reducing inflammation.
Q: Can I use Seroflo daily?
A: Yes, you should use Seroflo daily as prescribed by your doctor. It acts as a regular preventive treatment. Do not use it to relieve sudden asthma attacks.
Q: Is Seroflo a steroid?
A: Yes, it contains a corticosteroid called fluticasone propionate to reduce airway inflammation. It also includes salmeterol, a long-acting bronchodilator medicine that relaxes and opens your airways.
Conclusion
Seroflo 100 Rotacaps provides reliable respiratory management through its dual-action formulation. Guided by clinical supervision and regulated UK pharmacy supply, patients can safely manage chronic conditions.
References and Data Sources
- NICE. Asthma and COPD Clinical Guidelines. https://www.nice.org.uk
- NHS Health A-Z. Inhalers for Asthma and COPD. https://www.nhs.uk
Medical Disclaimer
This content serves purely to inform and does not stand in for guidance from a qualified medical professional. Before any treatment starts or is changed, a registered healthcare professional ought to be consulted.






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