Description
Axepta 18: Proven Atomoxetine 18mg ADHD Relief
Axepta 18 is a prescription-only medicine (POM) containing atomoxetine hydrochloride 18mg. It is bioequivalent to Strattera, the established UK reference brand.
Both contain identical active salt and deliver the same therapeutic effect.
| Brand | Active Ingredient | Strength | Manufacturer |
|---|---|---|---|
| Axepta 18 | Atomoxetine hydrochloride | 18mg | Intas Pharmaceuticals Limited |
| Strattera (UK Reference) | Atomoxetine hydrochloride | 18mg | Eli Lilly |
Medicine Composition
| Parameter | Details |
|---|---|
| Active Ingredient | Atomoxetine 18 mg |
| Drug Class | Selective Norepinephrine Reuptake Inhibitor (SNRI) |
Available Strengths
Axepta Is Also Offered in a Range of Higher Strengths Depending on Treatment Requirements:
- Axepta 10
- Axepta 20
- Axepta 25
- Axepta 40
- Axepta 60
Manufacturer
Intas Pharmaceuticals Limited.
Expiry Information
Expiry dates are supplied according to the actual batch provided at the time of purchase.
Mechanism of Action

Atomoxetine is a selective noradrenaline reuptake inhibitor (NRI). It blocks the reuptake of noradrenaline (a brain chemical that regulates attention and impulse control) into nerve cells. By raising noradrenaline availability in the prefrontal cortex, both concentration is improved and impulsivity is reduced. Unlike stimulant medicines, atomoxetine carries no controlled substance classification in the UK.
Clinical Uses
Axepta 18 is authorised for:
- ADHD in children aged six and over
- ADHD in adolescents within a broader treatment programme
- ADHD in adults where childhood symptoms continue causing impairment
- Patients are unable to tolerate stimulant ADHD medicines
Safety Information
| Category | Side Effect | Additional Guidance |
|---|---|---|
| Common Side Effects | Decreased appetite | |
| Common Side Effects | Nausea | |
| Common Side Effects | Headache | |
| Common Side Effects | Dry mouth | |
| Common Side Effects | Insomnia | |
| Common Side Effects | Dizziness | |
| Common Side Effects | Raised heart rate | |
| Serious Side Effects — Seek Urgent Medical Attention | Suicidal thoughts or self-harm | Particularly in children — contact NHS 111 or attend your nearest A&E without delay |
| Serious Side Effects — Seek Urgent Medical Attention | Severe allergic reaction | Rash, swelling, or breathing difficulty — attend your nearest A&E without delay |
| Serious Side Effects — Seek Urgent Medical Attention | Liver problems | Jaundice, dark urine, or abdominal pain — contact NHS 111 or attend your nearest A&E without delay |
| Serious Side Effects — Seek Urgent Medical Attention | Chest pain, palpitations, or fainting | Attend your nearest A&E without delay |
| Serious Side Effects — Seek Urgent Medical Attention | Hallucinations or psychotic symptoms | Contact NHS 111 or attend your nearest A&E without delay |
| Serious Side Effects — Seek Urgent Medical Attention | Prolonged or painful erections | In male patients — seek urgent medical attention without delay |
Report suspected reactions via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk.
Safety Advice
Liver Health
Atomoxetine may rarely cause liver injury. Stop Axepta 18 and seek medical advice if jaundice or abdominal pain develops.
Kidney Health
In patients with renal impairment, this medicine should be used with caution. Your prescriber will assess the suitability of the dosage individually.
Alcohol
Avoid alcohol entirely during treatment. It may worsen dizziness and cardiovascular side effects.
Driving
Axepta 18 may cause dizziness and fatigue. Until the effects of atomoxetine on your alertness are known, driving should be avoided.
Pregnancy
Axepta 18 is not recommended during pregnancy. Animal studies indicate developmental risks. Inform your prescriber immediately if pregnant or planning to conceive.
Breastfeeding
Atomoxetine may pass into breast milk. Axepta 18 is contraindicated whilst breastfeeding. Always consult your prescriber before use.
Accessing Treatment Responsibly
Axepta 18 is a POM. Always consult a qualified UK healthcare professional before starting or changing treatment.
Frequently Asked Questions
Q: What is the use of Axepta 18?
A: Children, adolescents, and adults with ADHD may all be prescribed Axepta 18 as part of their treatment plan. It improves attention, reduces impulsivity, and supports daily functioning. It is a prescription-only medicine containing atomoxetine 18mg.
Q: How does Axepta 18 work?
A: Axepta 18 blocks noradrenaline reuptake in the brain. This increases focus and reduces hyperactivity. It works continuously throughout the day without the peaks and troughs of stimulant medicines.
Q: Does Axepta make me sleepy?
A: Axepta 18 may cause fatigue or drowsiness in some patients. This often improves as your body adjusts. Speak to your doctor if tiredness significantly affects your daily activities.
Q: Can I take Axepta without food?
A: Yes. Food does not affect how well Axepta 18 works, meaning it can be taken with or without a meal. The capsule must always be swallowed whole, as chewing or opening it should be avoided at all times. Consistent daily timing supports steady atomoxetine levels in the bloodstream.
Conclusion
Axepta 18 (atomoxetine 18mg), manufactured by Intas Pharmaceuticals Limited, is a regulated non-stimulant POM bioequivalent to Strattera. It provides consistent all-day ADHD symptom control under qualified medical supervision. Always disclose your full medical history to your prescriber before starting treatment.
References
- NHS. ADHD: treatment. NHS.uk. [Accessed 2025]
- NICE. ADHD guideline NG87. [Accessed 2025]
- MHRA. Atomoxetine product information. GOV.UK. [Accessed 2025]
Medical Disclaimer
This article is for informational purposes only and does not replace professional medical advice. Always consult a registered healthcare professional before starting, changing, or stopping any prescribed medicine. In a medical emergency, call 999 or attend your nearest NHS A&E immediately.






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